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KMID : 0352419930120030351
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Keimyung Medical Journal
1993 Volume.12 No. 3 p.351 ~ p.358
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Alterations of Nerve conduction Velocities in Epileptics with Chronic Anticonvulsants Therapy
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이형
임정근/이동국/이상도/박영춘
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Abstract
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This study was performed to verify whether of not chronic anticonvulsants therapy(≥12 months) is associated with peripheral nerve dysfunction in epileptics.
Nerve conduction studies were done to 51 epileptics who had been taking long term anticonvulsants therapy over 12 months.
The mean age of epileptics was 23 years, and was composed of 29 men and 22 women.
The mean nerve conduction velocity(NCV) was not significantly different between epileptics and controls.
Compared phenytoin or carbamazepine monotherapy group with controls, the NCV was not significantly different in two groups, respectively.
In epileptics, the mean NCV was not significantly different between phenytoin and carbamazepine monotherapy group.
There was no significant relationship between NCV and duration of therapy with either phenytoin or carbamazepine.
In epileptics with phenytoin combined therapy, the mean median sensory NCV was significantly delayed than in those with phenytoin monotherapy.
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KEYWORD
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